When I had ITBS really bad, that walking up and down stairs took forever with lots of limping, the doctor told me to take Ibuprofen every 4 hours whether I was in pain or not to reduce inflammation to start healing. Which I did for the 3 weeks I was off running completely. I have not taken it to run though because I want to be attuned to any pain so I can STOP and not make it worse. coming back from ITBS has been a delicate dance for me that has involved cutting runs short if I feel pain and taking extra rest days if I feel it after a run, and that is probably the only reason (well, plus all the strengthening, stretching, rolling, PT, ect I've been doing) that I have not aggervated it to the point of having to take any more time off running than an extra rest day here and there since I first got it. If I was masking the pain and not noticing the nuances of the injury I may not be running today.