Lots of construction on Madison and running on that street to begin with is dangerous.  I have outlined my run to go around that this weekend.  I plan to go down Grandin Road to Edwards to Erie.  Thought I would just point this out to give you another option. 

21 Staples - Eden Park - Grandin Road - Erie - Kroger - Erie - Riverside - Staples

http://www.mapmyrun.com/route/us/oh/cincinnati/195126660805344223